Why Migraine in Fibromyalgia Syndrome Makes Life Harder
Living with fibromyalgia is already a full-time job—add migraines into the mix, and it can feel like you’re juggling flaming swords on a tightrope. I’ve been down that road, and let me tell you, the overlap between these two chronic conditions isn’t just frustrating—it’s deeply personal. What’s worse? Most people (even some doctors) don’t realize how intertwined migraines and fibromyalgia really are. If you’ve been bouncing between neurologists and rheumatologists, trying to explain the brain fog, head pain, and all that invisible discomfort—welcome, you’re not alone.
Understanding the Fibro-Migraine Connection

Fibromyalgia and migraines often team up to wreak havoc on the nervous system. And no, it’s not all in your head—well, technically it is, but not the way skeptics mean. Both conditions involve a complex web of overactive pain receptors, neurotransmitter imbalances, and heightened sensitivity to stimuli like noise, light, or even gentle touches.
Why Do They Occur Together So Often?
It’s not a coincidence. Studies show a high percentage of people with fibromyalgia also experience frequent migraines. Some researchers think it’s because of central sensitization, a process where your nervous system becomes extra sensitive to pain signals. That’s the short version. The longer version involves serotonin, inflammation, and your body’s stress response system playing a tug of war with your brain’s pain centers.
- Serotonin levels: Both conditions are linked to imbalances in serotonin, a chemical that helps regulate pain and mood.
- Inflammation: Chronic low-level inflammation may trigger both widespread pain and migraine attacks.
- Stress response: Constant stress can worsen both fibro flares and migraine intensity, especially in women.
And if you’re thinking, “That explains why my headaches are worse when my fibro acts up,” you’re exactly right.
Symptoms That Overlap (And Confuse)

Here’s where it gets messy. Fatigue, sensitivity to light and sound, brain fog, and even nausea—are they from your migraine or your fibromyalgia? The overlap can make diagnosis and treatment tricky.
- Brain fog: That feeling like your head’s full of cotton? Common in both.
- Sensory overload: Bright lights, loud sounds, strong smells—migraine and fibromyalgia both hate them.
- Neck and jaw pain: Migraines can start here. So can fibro flare-ups.
Sometimes, you feel like you’re chasing shadows trying to figure out which condition is the root cause. And often, it’s both working in tandem. Neck pain during migraine attacks is particularly common in fibro patients, and not addressing it holistically can make recovery slow and painful.
How Hormones and Sleep Factor In

Two words: unpredictable chaos. Hormonal shifts and bad sleep are migraine and fibromyalgia’s favorite triggers. If you’ve ever had a killer migraine the day before your period or felt like your body betrayed you after three nights of bad sleep, you’re not imagining it.
Research indicates that hormonal imbalances—especially estrogen fluctuations—can amplify pain signals in people with fibromyalgia. Add migraines to the mix, and those signals go nuclear. For women in their 30s to 50s, this is a perfect storm. Lack of restorative sleep only makes it worse.
One of the most helpful changes I made was tracking both my cycle and sleep patterns using a journal. It helped me spot patterns I would’ve never noticed. You might want to start your own migraine diary—not for your doctor (although that’s helpful), but for your own sanity.
Treatment Isn’t One-Size-Fits-All

Let’s be honest: the traditional healthcare system isn’t great at treating chronic overlapping conditions. You might be prescribed a migraine-specific medication that worsens your fibro fatigue—or vice versa. That’s why a multi-disciplinary, personalized approach is essential.
What’s Been Helpful for Me
Through trial, error, and a little desperation, I’ve found a few things that actually helped:
- CGRP inhibitors: These newer migraine medications have been a game-changer. Worth asking your doc about.
- Low-impact exercise: Think yoga, tai chi, gentle walking. Movement reduces fibro pain and eases tension headaches.
- CBT (Cognitive Behavioral Therapy): Helped me reframe the stress–pain cycle. Also helped me sleep better.
- Supplements: Magnesium and CoQ10 help with both muscle relaxation and migraine prevention. But ask your doctor first.
For those navigating both migraines and fibromyalgia, some non-drug treatments like acupuncture and CBT show real promise. They address both the emotional toll and physical pain.
Some days are harder than others, but understanding the shared roots of these conditions gives you more power to fight back.
Where to Go Next

If you’ve made it this far, chances are you’re either dealing with fibromyalgia, migraines, or both—and you’re hungry for answers. The key is learning how these two conditions play off each other, and using that knowledge to build a more effective, personalized treatment strategy.
To dig deeper into tailored strategies for chronic migraine treatment, check out our detailed guide on migraine treatments. And for a broader understanding of everything migraine-related, head to the main migraine resource hub.
For more on how fibromyalgia complicates neurological conditions like migraine, resources from Mayo Clinic and NINDS are excellent for deep dives. Always cross-reference with what you’re experiencing. Nobody knows your body better than you.
Daily Strategies That Actually Work

One of the biggest game-changers for me wasn’t a new prescription—it was small lifestyle adjustments. When you live with both fibromyalgia and migraines, the usual “rest more” advice doesn’t cut it. You need structure, flexibility, and forgiveness. A weird mix, but trust me, it works.
Here’s what’s helped keep my symptoms from spiraling:
- Scheduled downtime: I literally block time on my calendar to do nothing. No guilt. No distractions.
- Hydration: It sounds basic, but dehydration has triggered more migraines for me than I’d like to admit.
- Blue light filters: I swear by them. Especially during screen-heavy days. You might also try migraine-friendly lighting.
- Meal consistency: Skipping meals = recipe for disaster. I now treat eating like medicine—non-negotiable.
Finding your personal triggers is a marathon, not a sprint. I used to push through warning signs—bad idea. Now, I treat even mild flares like a red flag. That small mindset shift alone has saved me weeks of recovery time.
The Mind-Body Connection is Real

I used to roll my eyes when people talked about “mind-body harmony.” Then I tried breathwork out of desperation one bad pain day—and it helped. Not a cure, but it softened the edge. When your nervous system is constantly in fight-or-flight mode, calming it can interrupt the feedback loop that makes pain spiral.
Tools that worked for me:
- Guided meditation apps: Five minutes can make a difference. Try pairing it with aromatherapy.
- Stretching: I follow short routines like these stretching techniques to loosen tension that builds up in my neck and shoulders.
- Journaling: Not daily, but often enough to track patterns or vent emotionally.
Chronic pain isn’t just a physical experience—it’s mental, emotional, even social. If you’re always “pushing through,” take a beat. Slowing down isn’t weakness. It’s strategy.
Hormonal Shifts Make It Worse (But Also Explain A Lot)

Women, especially during perimenopause or with irregular cycles, often notice a surge in symptoms. Fibromyalgia already messes with sleep and energy levels, and hormones just stir the pot further. If your migraines are worse during your cycle, you’re not alone—it’s incredibly common.
There’s even a specific term for this: menstrual migraines. Add fibromyalgia to the mix, and it can feel like your body is operating on a completely different planet some days.
Personally, I found some relief by working with a gynecologist who understood chronic illness and was open to adjusting treatments month-to-month. That collaborative approach made a massive difference, especially in reducing hormonal spikes and subsequent flares.
When the Healthcare System Falls Short

Let’s talk about the elephant in the room: how exhausting it is trying to get help. Most fibromyalgia patients with migraines end up seeing a neurologist, rheumatologist, GP, and maybe even a therapist—just to cobble together basic care. It’s maddening.
In my experience, the most progress came when I became my own advocate. I started bringing symptom journals to every appointment, researched migraine-focused neurologists who had experience with fibromyalgia, and gently but firmly pushed for more collaborative care.
Some clinics now use multi-disciplinary teams—if you can find one of these, grab the opportunity. It takes the burden off you to play medical middleman.
What the Research is Finally Catching Up To

Here’s the good news: awareness is growing. More studies are looking at shared neural pathways, common inflammation markers, and overlapping diagnostic criteria for both conditions. One recent paper highlighted how both fibro and migraine patients tend to have abnormal pain modulation responses. Translation? Our nervous systems process pain differently—and more intensely.
There’s also promising research into CGRP inhibitors and how they may help fibromyalgia patients with co-occurring migraines. These drugs block pain signal transmission without the sedative side effects of older meds. Worth asking about, especially if nothing else is working.
For the latest overviews and up-to-date studies, I’ve found NCBI and CDC to be reliable and surprisingly readable when you dive in.
You’re Not Alone—And You’re Not Imagining This

It’s easy to feel isolated with invisible illnesses, especially when your pain doesn’t show up on a scan. But here’s the truth: your symptoms are valid, your experience is real, and there’s a growing body of research and resources to back you up.
Living with fibromyalgia and migraines is a balancing act that shifts week to week, sometimes hour to hour. You’re allowed to adapt, rest, push, pause—whatever you need. Managing these conditions isn’t about “fixing” yourself. It’s about learning how to work with your body instead of against it.
For a more complete look at managing the intersection of pain, lifestyle, and triggers, take a look at our broader overview on comorbid migraine conditions.
And if you’re just starting this journey, or feel like you’ve hit a wall, revisit our primary guide on migraines and headaches. It’s a good place to reset, reflect, and remind yourself—you’ve got options.

Bianca Nala is a compassionate Nurse Practitioner with a strong background in primary and respiratory care. As a health writer for Healthusias.com, she combines her clinical expertise with a talent for clear, relatable storytelling to help readers better understand their health. Bianca focuses on topics like asthma, COPD, chronic cough, and overall lung health, aiming to simplify complex medical topics without losing accuracy. Whether she’s treating patients or writing articles, Bianca is driven by a single goal: making quality healthcare knowledge accessible to everyone.






